Fungi



BCRC Number: 31840
Organism: Cunninghamella echinulata var. echinulata
Author: (Thaxter) Thaxter
History: << DSM << NRRL
Other Collection No.: ATCC 36190 ;DSM 1905 ;NRRL 11498 ;NRRL 3655 ;NRRL A-11498
Characterization:
Biostransformation of : sesquiterpene lactone costunolide--M18;
antitumor agents--M606;
Production of : gamma-linolenic acid--M2480, M2482, M2486;
leucomycin derivativesU. S. Pat. 3,784,447
magnamycin
niddamycin
Others: conversion of antitumor alkaloid acronycine to 9-hydroxyacronycine--M156
Growth Conditions: 25°C
Oxygen Requirement: Aerobic
Biosafety Level: 1
Shipping/Field/Price:
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References



M156
Betts, R. E., D. E. Walters, and J. P. Rosazza. 1974. Microbial transformations of antitumor compounds. 1. Conversion of Acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602.
M18
Clark, A. M., and C. D. Hufford. 1979.. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979:: 3022-3028..
M2480
Chen, H.-C., and T.-M. Liu. 1997. Inoculum effects on the production of gamma-linolenic acid by the shake culture of Cunninghamella echinulata CCRC 31840. Enzyme & Microbial Technology 21: 137-142.
M2482
Chen, H.-C., and C.-C. Chang. 1996. Production of gamma-linolenic acid by the fungus Cunninghamella echinulata CCRC 31840. Biotechnology Progress 12: 338-341.
M2486
Chen, H.-C., and C.-C. Chang. 1994. Screening of microbes for the production of polyunsaturated fatty acids. Journal of the Chinese Agricultural Chemical Society 32: 33-46.
M606
Chien, M. M., and J. P. Rosazza. 1979. Microbial transformations of natural antitumor agents. 9. o-demethylation of 9-methoxyellipticine. J. Nat. Prod. 42: 643-647.
 

Medium



36
POTATO DEXTROSE AGAR (PDA)
Diced potatoes200.0 g
Glucose20.0 g
Agar15.0 g
Distilled water1.0 L
Boil finely diced potatoes in 500 ml of water until thoroughly cooked, filter through cheesecloth and add water to filtrate to 1.0 L. The agar is dissolved in the filtrate by heating, and the glucose is added prior to sterilization.

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